Umbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis

Autor: Colleen Ovelman, Philippa Middleton, Judith Streak Gomersall, Slavica Berber, Susan McDonald, Georg M. Schmölzer, Susan Niermeyer, Peter G Davis, Walid El-Naggar, Roger F. Soll
Rok vydání: 2021
Předmět:
Zdroj: Pediatrics. 147
ISSN: 1098-4275
0031-4005
Popis: CONTEXT:The International Liaison Committee on Resuscitation prioritized scientific review of umbilical cord management at term and late preterm birth.OBJECTIVE:To assess effects of umbilical cord management strategies (clamping timing and cord milking) in infants ≥34 weeks’ gestational age.DATA SOURCES:Cochrane Central Register of Controlled Trials, Medline, PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, and trial registries searched July 2019.STUDY SELECTION:Two authors independently assessed eligibility of randomized controlled trials.DATA EXTRACTION:Two authors independently extracted data and assessed evidence certainty (Grading of Recommendations Assessment, Development and Evaluations).RESULTS:We identified 46 studies (9159 women and their infants) investigating 7 comparisons. Compared with early cord clamping (ECC) LIMITATIONS:Incompleteness and low certainty of findings limit applicability.CONCLUSIONS:Compared with ECC, DCC or cord milking increases hemoglobin and hematocrit immediately after birth in infants ≥34 weeks’ gestational age. The uncertain effects of DCC and cord milking compared with ECC on major morbidities limit usefulness of available evidence for policy and practice.
Databáze: OpenAIRE