Fever after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction is associated with adverse outcomes
| Autor: | Hyuck-Jun Yoon, Yoon-Nyun Kim, Seung Ho Hur, Chang-Wook Nam, Kwon-Bae Kim, Hong-Won Shin, In-Sung Chung, Hyoung-Seob Park, Ho-Myung Lee, Hyungseop Kim, Hyun-Ok Cho, Yun-Kyeong Cho |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Fever medicine.medical_treatment Myocardial Infarction Revascularization Electrocardiography Percutaneous Coronary Intervention Predictive Value of Tests Recurrence Risk Factors Diabetes mellitus Internal medicine medicine Prevalence ST segment Humans Myocardial infarction Risk factor Aged Retrospective Studies Ejection fraction business.industry Percutaneous coronary intervention Middle Aged medicine.disease Prognosis Cardiology Female Cardiology and Cardiovascular Medicine business Mace Biomarkers |
| Zdroj: | International journal of cardiology. 170(3) |
| ISSN: | 1874-1754 |
| Popis: | Background Fever is a common finding after primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction (STEMI). However, its prognostic value is not validated yet. Objectives This study sought to evaluate the impact of fever after PPCI in STEMI on adverse clinical outcomes. Methods Five hundred fourteen consecutive patients who underwent PPCI due to STEMI were enrolled. Body temperature (BT) was checked every 6h for 5days after PPCI. Patients were divided into two groups according to the highest quartile of peak BT; peak BT≤37.6°C (control group) and peak BT>37.6°C (fever group). Rates of 1-year major adverse cardiovascular events (MACE; death, myocardial infarction, any revascularization) were compared. Results The prevalence of fever group (peak BT>37.6°C) was 24.7% (127/514). White blood cell count, highly sensitive C-reactive protein and serum cardiac troponin I level were higher in fever group than control group (12,162±4199/μL vs. 10,614±3773/μL, p p =0.001, 16.7±36.9ng/dl vs. 8.70±26.2ng/dl, p =0.027, respectively). The frequency of a history of previous myocardial infarction and left ventricular ejection fraction was lower in fever group (0.0% vs. 4.7%, p =0.010; 47±8 % vs. 49±9 %, p =0.002, respectively). There was no significant difference in angiographic characteristics between 2 groups. 1-year MACE rates were higher in fever group (11.0% vs. 4.7%, p =0.010). Multivariate analysis revealed fever (OR 2.358, 95% CI 1.113–4.998, p =0.025), diabetes mellitus as risk factor (2.227, 1.031–4.812, 0.042), and left anterior descending artery as infarct related artery (2.443, 1.114–5.361, 0.026) as independent predictors for 1-year MACE. Conclusions Fever after PPCI in patients with STEMI is frequently developed and it can predict adverse clinical outcome. |
| Databáze: | OpenAIRE |
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