Evaluation of day of hatch exposure to various Enterobacteriaceae on inducing gastrointestinal inflammation in chicks through two weeks of age
| Autor: | K.M. Chasser, Lisa Bielke, E. Winson, K. McGovern, M. Trombetta, A.F. Duff, W.N. Briggs, B.D. Graham, Denise Russi Rodrigues |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
food.ingredient
Opportunistic infection Orosomucoid Inflammation Biology SF1-1100 03 medical and health sciences food Animal science Enterobacteriaceae gastrointestinal inflammation Yolk IMMUNOLOGY HEALTH AND DISEASE medicine opportunistic disease Escherichia coli Animals Yolk sac Poultry Diseases 030304 developmental biology Citrobacter 0303 health sciences Salmonella Infections Animal Inoculation 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine medicine.disease biology.organism_classification 040201 dairy & animal science Animal culture medicine.anatomical_structure Salmonella enteritidis biology.protein Animal Science and Zoology medicine.symptom alpha-1-acid glycoprotein Chickens |
| Zdroj: | Poultry Science Poultry Science, Vol 100, Iss 7, Pp 101193-(2021) |
| ISSN: | 1525-3171 0032-5791 |
| Popis: | Inappropriate microbial colonization can induce gastrointestinal (GI) inflammation may predispose poultry to opportunistic infections and reduce growth performance. Four independent experiments were completed to test ability of select Enterobacteriaceae isolates to induce GI inflammation. Experiments 1 and 2 included a non-inoculated control (NC), and a low (L), medium (M), or high (H) day of hatch (DOH) oral inoculation level. In experiment 1, birds in L1, M1, and H1 received 102 to 104 CFU of a mixed dose of 2 species of Citrobacter and Salmonella Enteritidis LB (SE). In experiment 2, birds in L2, M2, and H2 received 103 to 105 CFU of E. coli LG (LG) and included NC. Body weight was recorded on d 0, 7, and 14, with blood collected for chicken serum alpha-1-acid glycoprotein (A1GP) measurements on d14. Neither experiment resulted in differences in BWG, however, A1GP was increased (P < 0.05) on d 14 when DOH inoculation dose 103 CFU/chick was used compared to NC. This observed increase in A1GP resulted in selection of 103 CFU/chick for DOH inoculation in experiments 3 and 4. Experiment 3 consisted of NC, E. coli Huff (Huff), and SE. On d 0, 7 and 15, BW was measured, with blood collected on d 15 for A1GP. Both d 15 A1GP and BWG from d 7 to 15 were reduced in inoculated chicks, Huff and SE, in experiment 3 (P < 0.05). Experiment 4 evaluated NC and LG with BW measured on d 0, 2, 7 and 14. Yolk sacs were evaluated for retention and bacterial enumeration, and blood for serum A1GP were collected on d 2 and 14. Experiment 4 resulted in no differences in yolk sac parameters or A1GP, whereas there was an increase in BWG for LG from d 0 to 14 (P < 0.05). When evaluated over time, serum A1GP increased between d 2 and d 14 by nearly 46% in LG, compared to negligible changes in NC (P = 0.111). Mild GI inflammation induced by early Enterobacteriaceae exposure may not drastically impact growth or inflammation parameters but may increase susceptibility to opportunistic infection necessitating further study of this model. |
| Databáze: | OpenAIRE |
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