The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium
| Autor: | James M. Anderson, Frederick L. Tyson, Linda S. Birnbaum, Lisa H. Chadwick, John S. Satterlee, Kim McAllister, Ananda L. Roy, Elizabeth L. Wilder, Nora D. Volkow, Jill M. Beaver |
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| Rok vydání: | 2019 |
| Předmět: |
Epigenomics
Engineering Financial Management education Reviews Review Epigenesis Genetic 03 medical and health sciences 0302 clinical medicine Common fund Humans GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) Molecular Biology 030304 developmental biology 0303 health sciences Multidisciplinary business.industry NIH Roadmap Epigenome Data science United States 3. Good health National Institutes of Health (U.S.) SciAdv reviews business 030217 neurology & neurosurgery |
| Zdroj: | Science Advances |
| ISSN: | 2375-2548 |
| Popis: | We outline the reasons why the Roadmap Epigenomics Program, as a group science effort, is a success story. The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort. |
| Databáze: | OpenAIRE |
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