Remission of relapsing childhood nephrotic syndrome with mycophenolate mofetil
| Autor: | Myron Susin, Carolyn Abitbol, Manju Chandra |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Nephrotic Syndrome Cyclophosphamide medicine.medical_treatment Drug Resistance Gastroenterology Focal segmental glomerulosclerosis Recurrence Internal medicine medicine Humans Minimal change disease Chemotherapy business.industry Remission Induction Glomerulonephritis Mycophenolic Acid medicine.disease Tacrolimus Surgery Nephrology Child Preschool Retreatment Pediatrics Perinatology and Child Health Toxicity business Nephrotic syndrome Immunosuppressive Agents medicine.drug |
| Zdroj: | Pediatric Nephrology. 14:224-226 |
| ISSN: | 1432-198X 0931-041X |
| Popis: | We report a 21-year-old male with childhood-onset familial nephrotic syndrome and frequent relapses who manifested toxicity or treatment resistance to corticosteroids, cyclophosphamide, cyclosporin-A, and tacrolimus. Monotherapy with mycophenolate mofetil (MMF) resulted in maintenance of clinical remission for 14 months without noticeable toxicity, while allowing resolution of steroid-induced side effects. Our observation suggests that MMF may be useful in maintaining remission in nephrotic patients who manifest toxicity to standard immunosuppressive agents. |
| Databáze: | OpenAIRE |
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