An Improved Stereocontrolled Route to cis-Erythrinanes by Combined Intramolecular Strecker and Bruylants Reaction

Autor:	Christian Ettmayr, Eberhard Reimann
Rok vydání:	2005
Předmět:	chemistry.chemical_classification Turn (biochemistry) Aldimine Stereochemistry Chemistry Intramolecular force Ethylamines Condensation General Chemistry General Medicine Medicinal chemistry
Zdroj:	ChemInform. 36
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200502209
Popis:	Condensation of (2-iodophenyl)ethylamines with cyclohexanoylacetaldehyde provided the corresponding aldimines which were reduced yielding secondary phenethylcyclohexanoylethylamines. These in turn were appropriate intermediates to prepare several erythrinanes by a sequential intramolecular Strecker and intramolecular Bruylants reaction. In contrast, the C-ring homologue schelhammeranes were not available on this route.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da7f4e715478944e37f44887a61bf5b https://doi.org/10.1002/chin.200502209 Zobrazit plný text záznamu Plný text