Signaling in Sperm: More Different than Similar
| Autor: | Ulrich Benjamin Kaupp, Timo Strünker |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Gene isoform Cell signaling Biology Models Biological Ion Channels 03 medical and health sciences 0302 clinical medicine Botany Animals Humans Receptor Ion channel Mammals Cellular pathways Cell Biology Sensory cell Spermatozoa Sperm Cell biology 030104 developmental biology Fertilization 030217 neurology & neurosurgery Function (biology) Signal Transduction |
| Zdroj: | Trends in Cell Biology. 27:101-109 |
| ISSN: | 0962-8924 |
| Popis: | For a given sensory cell type, signaling motifs are rather uniform across phyla. By contrast, sperm from different species use diverse repertoires of sperm-specific signaling molecules and even closely related protein isoforms feature different properties and serve different functions. This surprising diversity has consequences for strategies in fertilization research and it will take some time to get the big picture. We discuss the function of receptors, ion channels, and exchangers embedded in cellular pathways from different sperm species. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect