Supplementary Figures 1 - 3 from RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors

Autor: Roman Perez-Soler, Bilal Piperdi, Vincent A. Miller, Philip J. Stephens, Matthew Hawryluk, Geoff Otto, Doron Lipson, Roman Yelensky, Kira Gritsman, Yiting Yu, Jidong Shan, Changcheng Zhu, Edward L. Schwartz, Sanjay Goel, Abraham Chachoua, Cristina Montagna, Amit Verma, Huijie Liu, Siraj M. Ali, Balazs Halmos, Xuewen Liu, Kai Wang, Jeffrey S. Ross, Yiyu Zou, Haiying Cheng
Rok vydání: 2023
Popis: Supplementary Figure 1 shows RICTOR amplification/overexpression in the index patient by FISH and IHC. Supplementary Figure 2 shows analysis of TCGA database for RICTOR alteration in all types of cancers, including NSCLC. Supplementary figure 3A shows the gene alterations in each individual with RICTOR-amplified tumors. 3B shows the absolute and relative frequency of each gene alteration found in RICTOR-amplified lung cancer samples from FM NGS database.
Databáze: OpenAIRE