Triggering of acute coronary occlusion by episodes of anger
| Autor: | Elizabeth Shaw, Thomas Buckley, Soon Y. Soo Hoo, Geoffrey H. Tofler, Judith Fethney, Peter S Hanson |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment media_common.quotation_subject Myocardial Infarction Anger Critical Care and Intensive Care Medicine behavioral disciplines and activities Surveys and Questionnaires Internal medicine mental disorders medicine Humans Myocardial infarction media_common business.industry General Medicine Thrombolysis Middle Aged Precipitating Factors medicine.disease Confidence interval Coronary Occlusion Coronary occlusion Relative risk Acute Disease behavior and behavior mechanisms Cardiology Physical therapy Anxiety Female medicine.symptom Personality Assessment Inventory Cardiology and Cardiovascular Medicine business psychological phenomena and processes |
| Zdroj: | European Heart Journal: Acute Cardiovascular Care. 4:493-498 |
| ISSN: | 2048-8734 2048-8726 |
| DOI: | 10.1177/2048872615568969 |
| Popis: | The aim of this study was to report the association between episodes of anger and acute myocardial infarction (MI) in patients with angiographically confirmed coronary occlusion.313 participants with acute coronary occlusion (Thrombolysis In Myocardial Infarction 0 or 1 at emergency angiography) reported frequency of anger episodes in the 48 h prior to MI. In primary analysis, anger exposures within 2 h and 2-4 h prior to symptom onset were compared with subjects' own usual yearly exposure to anger using case-crossover methodology. Anger level ≥5 (on an anger scale of 1-7) was reported by seven (2.2%) participants within 2 h of MI. Compared with usual frequency, the relative risk of onset of MI symptoms occurring within 2 h of anger level ≥5 (defined as very angry) was 8.5 (95% confidence interval 4.1-17.6). Anger level5 was not associated with onset of MI symptoms. Compared with 24-26 h pre MI, anxiety scores75th percentile on State-Trait Personality Inventory were associated with a relative risk of 2.0 (95% confidence interval 1.1-3.8) and in those above the 90th percentile, the relative risk of MI symptom onset was 9.5 (95% confidence interval 2.2-40.8).Findings confirm that episodes of intense anger, defined as being 'very angry, body tense, clenching fists or teeth' (within 2 h) are associated with increased relative risk for acute coronary occlusion. Additionally, increased anxiety was associated with coronary occlusion. Further study, including the role of potential modifiers, may provide insight into prevention of MI during acute emotional episodes. |
| Databáze: | OpenAIRE |
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