Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments, in 3 year old children
| Autor: | Nicole Ferret, Gunilla Malm, Hooi Kuan Tan, Ruth Gilbert, Katherine Freeman, Wilma Buffolano, Andrea R. Prusa, Alison Salt, Dorthe Schmidt |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
Parents Pediatrics medicine.medical_specialty Multivariate analysis Developmental Disabilities Vision Disorders Prenatal diagnosis Child Behavior Disorders Anxiety Toxoplasmosis Congenital 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Prenatal Diagnosis Surveys and Questionnaires Medicine Humans 030212 general & internal medicine Pediatrics Perinatology and Child Health Prospective Studies Association (psychology) Prospective cohort study Psychiatry business.industry lcsh:RJ1-570 lcsh:Pediatrics medicine.disease Prognosis Toxoplasmosis 3. Good health Child Preschool Pediatrics Perinatology and Child Health Cohort Multivariate Analysis Female medicine.symptom business Research Article |
| Zdroj: | BMC Pediatrics BMC Pediatrics, Vol 5, Iss 1, p 23 (2005) |
| ISSN: | 1471-2431 |
| Popis: | Background Information is lacking on the effects of congenital toxoplasmosis on development, behavior, and impairment in later childhood, as well as on parental concerns and anxiety. This information is important for counselling parents about the prognosis for an infected child and for policy decisions on screening. Methods We prospectively studied a cohort of children identified by screening for toxoplasmosis in pregnant women or neonates between 1996 and 2000 in ten European centers. At 3 years of age, parents of children with and without congenital toxoplasmosis were surveyed about their child's development, behavior, and impairment, and about parental concerns and anxiety, using a postal questionnaire. Results Parents of 178/223 (80%) infected, and 527/821 (64%) uninfected children responded. We found no evidence that impaired development or behavior were more common in infected children, or that any potential effect of congenital toxoplasmosis was masked by prenatal treatment. Parents of infected children were significantly more anxious and reported more visual problems in their children. Conclusion On average, children aged three to four years with congenital toxoplasmosis identified by screening and treated during infancy in this European setting had risks of abnormal development and behavior similar to uninfected children. Parental anxiety about infected children needs to be addressed by clinicians. Future studies with longer follow up and clinician-administered assessments may be better able to detect any subtle differences in child outcomes. |
| Databáze: | OpenAIRE |
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