Laminar fMRI
| Autor: | Lars Muckli, Floris P. de Lange, Samuel J. D. Lawrence, Elia Formisano |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cognitive Neuroscience OCULAR DOMINANCE COLUMNS SPATIAL ATTENTION ORGANIZATION Cognitive neuroscience Feedforward Feedback 03 medical and health sciences 0302 clinical medicine WORKING-MEMORY Cortex (anatomy) medicine Animals Humans Sensory cortex Visual cortex BRAIN Brain Mapping V1 Action intention and motor control Working memory Cortical layers NEGATIVE BOLD 180 000 Predictive Brain Human brain Neurophysiology Top-down Magnetic Resonance Imaging MODEL PRIMARY VISUAL-CORTEX 030104 developmental biology medicine.anatomical_structure Neurology nervous system Bottom-up Psychology Neuroscience 030217 neurology & neurosurgery Ocular dominance column Laminar fMRI NEURAL ACTIVITY |
| Zdroj: | NeuroImage, 197, 785-791 NeuroImage, 197, pp. 785-791 |
| ISSN: | 1053-8119 |
| DOI: | 10.1016/j.neuroimage.2017.07.004 |
| Popis: | Contains fulltext : 221628.pdf (Publisher’s version ) (Closed access) The cortex is a massively recurrent network, characterized by feedforward and feedback connections between brain areas as well as lateral connections within an area. Feedforward, horizontal and feedback responses largely activate separate layers of a cortical unit, meaning they can be dissociated by lamina-resolved neurophysiological techniques. Such techniques are invasive and are therefore rarely used in humans. However, recent developments in high spatial resolution fMRI allow for non-invasive, in vivo measurements of brain responses specific to separate cortical layers. This provides an important opportunity to dissociate between feedforward and feedback brain responses, and investigate communication between brain areas at a more fine- grained level than previously possible in the human species. In this review, we highlight recent studies that successfully used laminar fMRI to isolate layer-specific feedback responses in human sensory cortex. In addition, we review several areas of cognitive neuroscience that stand to benefit from this new technological development, highlighting contemporary hypotheses that yield testable predictions for laminar fMRI. We hope to encourage researchers with the opportunity to embrace this development in fMRI research, as we expect that many future advancements in our current understanding of human brain function will be gained from measuring lamina-specific brain responses. 7 p. |
| Databáze: | OpenAIRE |
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