16S rRNA gene sequencing data of the upper respiratory tract microbiome in the SARS-CoV-2 infected patients

Autor: Julia Galeeva, Vladislav Babenko, Ramiz Bakhtyev, Vladimir Baklaushev, Larisa Balykova, Pavel Bashkirov, Julia Bespyatykh, Anna Blagonravova, Daria Boldyreva, Dmitry Fedorov, Ilshat Gafurov, Raushaniya Gaifullina, Elena Galova, Alina Gospodaryk, Elena Ilina, Konstantin Ivanov, Daria Kharlampieva, Polina Khromova, Ksenia Klimina, Konstantin Kolontarev, Nadezhda Kolyshkina, Andrey Koritsky, Vyacheslav Kuropatkin, Vasily Lazarev, Alexander Manolov, Valentin Manuvera, Daria Matyushkina, Maxim Morozov, Ekaterina Moskaleva, Varvara Musarova, Oleg Ogarkov, Elizaveta Orlova, Alexander Pavlenko, Alla Petrova, Natalia Pozhenko, Dmitry Pushkar, Alexander Rumyantsev, Sergey Rumyantsev, Vladimir Rumyantsev, Lyubov Rychkova, Alexander Samoilov, Irina Shirokova, Vyacheslav Sinkov, Svetlana Solovieva, Elizaveta Starikova, Polina Tikhonova, Galina Trifonova, Alexander Troitsky, Alexander Tulichev, Yuri Udalov, Anna Varizhuk, Alexander Vasiliev, Vladimir Veselovsky, Rinat Vereshchagin, Alexey Volnukhin, Gaukhar Yusubalieva, Vadim Govorun
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Data in Brief
Data in Brief, Vol 40, Iss, Pp 107770-(2022)
ISSN: 2352-3409
Popis: The SARS-CoV-2 pandemic is a big challenge for humanity. The COVID-19 severity differs significantly from patient to patient, and it is important to study the factors protecting from severe forms of the disease. Respiratory microbiota may influence the patient's susceptibility to infection and disease severity due to its ability to modulate the immune system response of the host organism. This data article describes the microbiome dataset from the upper respiratory tract of SARS-CoV-2 positive patients from Russia. This dataset reports the microbial community profile of 335 human nasopharyngeal swabs collected between 2020-05 and 2021-03 during the first and the second epidemic waves. Samples were collected from both inpatients and outpatients in 4 cities of the Russian Federation (Moscow, Kazan, Irkutsk, Nizhny Novgorod) and sequenced using the 16S rRNA gene amplicon sequencing of V3-V4 region. Data contains information about the patient such as age, sex, hospitalization status, percent of damaged lung tissue, oxygen saturation (SpO2), respiratory rate, need for supplemental oxygen, chest computer tomography severity score, SARS-CoV-2 lineage, and also information about smoking and comorbidities. The amplicon sequencing data were deposited at NCBI SRA as BioProject PRJNA751478.
Databáze: OpenAIRE