Dietary Montmorillonite Improves the Intestinal Mucosal Barrier and Optimizes the Intestinal Microbial Community of Weaned Piglets
| Autor: | Xueling Gu, Han Liu, Jing Zhao, Wenju Zhang, Xi Ma, Cunxi Nie, Congmin Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
intestinal bacteria community Crypt lcsh:QR1-502 Ileum montmorillonite Gut flora medicine.disease_cause digestive system Microbiology lcsh:Microbiology Jejunum 03 medical and health sciences Animal science Lactobacillus intestinal mucosal barrier medicine Eubacterium weaned piglets 030304 developmental biology Original Research 0303 health sciences growth performance biology Streptococcus Chemistry digestive oral and skin physiology 0402 animal and dairy science 04 agricultural and veterinary sciences biology.organism_classification 040201 dairy & animal science medicine.anatomical_structure Duodenum |
| Zdroj: | Frontiers in Microbiology Frontiers in Microbiology, Vol 11 (2020) |
| ISSN: | 1664-302X |
| Popis: | The study investigated the impact of dietary montmorillonite on the growth performance, intestinal mucosal barrier, and microbial community in weaned piglets with control group (CON) and dietary supplementation of 0.2% montmorillonite (0.2% M). Compared with the CON group, 0.2% M feed in the diet increased the average daily gain (ADG) on days 15–35 and day 1–35 and the average daily feed intake on days 1–35 (ADFI) (0.05 < P < 0.1). Besides, higher villus height of the duodenum and jejunum and lower crypt depth of duodenum and colon were revealed in the 0.2% M group than in the CON group (P < 0.05). Moreover, the V/C (ratio of the villus height and crypt depth) in the 0.2% M group was increased compared to that in the CON group both from the duodenum and ileum (P < 0.05). The relative mRNA expression of mucin-1, ITGB1 (β1-integrins), and PKC (protein kinase C) of ileum in the 0.2% M group were upregulated (P < 0.05) compared to that in the CON group. The digesta sample of ileum from piglets in the 0.2% M group contained greater (P < 0.05) intestinal bacterial diversity and abundances of probiotics, such as Streptococcus, Eubacterium_rectale_group, and Lactobacillus, which could promote the synthesis of carbon-containing biomolecules. Overall, dietary supplementation of 0.2% M was shown to have a tendency to improve the growth performance of weaned piglets and may enhance their intestinal mucosal barrier function via altering the gut microbiota. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|