Priming Effects of Water Immersion on Paired Associative Stimulation-Induced Neural Plasticity in the Primary Motor Cortex
| Autor: | Yasuhiro Baba, Atsuo Maruyama, Koyuki Ikarashi, Koya Yamashiro, Daisuke Sato, Yudai Yamazaki, Hideaki Onishi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Health Toxicology and Mutagenesis medicine.medical_treatment Long-Term Potentiation lcsh:Medicine Biology Motor Activity Article 03 medical and health sciences 0302 clinical medicine Neuroplasticity medicine Humans Latency (engineering) Evoked potential 030304 developmental biology 0303 health sciences Neuronal Plasticity lcsh:R Public Health Environmental and Occupational Health Motor Cortex m1 plasticity Water Long-term potentiation Evoked Potentials Motor Hand Transcranial Magnetic Stimulation short latency afferent inhibition Transcranial magnetic stimulation Cholinergic water immersion Female pas25 Primary motor cortex Neuroscience Priming (psychology) 030217 neurology & neurosurgery |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 1, p 215 (2019) International Journal of Environmental Research and Public Health Volume 17 Issue 1 |
| ISSN: | 1660-4601 |
| Popis: | We aimed to verify whether indirect-wave (I-wave) recruitment and cortical inhibition can regulate or predict the plastic response to paired associative stimulation with an inter-stimulus interval of 25 ms (PAS25), and also whether water immersion (WI) can facilitate the subsequent PAS25-induced plasticity. To address the first question, we applied transcranial magnetic stimulation (TMS) to the M1 hand area, while alternating the direction of the induced current between posterior-to-anterior and anterior-to-posterior to activate two independent synaptic inputs to the corticospinal neurons. Moreover, we used a paired stimulation paradigm to evaluate the short-latency afferent inhibition (SAI) and short-interval intracortical inhibition (SICI). To address the second question, we examined the motor evoked potential (MEP) amplitudes before and after PAS25, with and without WI, and used the SAI, SICI, and MEP recruitment curves to determine the mechanism underlying priming by WI on PAS25. We demonstrated that SAI, with an inter-stimulus interval of 25 ms, might serve as a predictor of the response to PAS25, whereas I-wave recruitment evaluated by the MEP latency difference was not predictive of the PAS25 response, and found that 15 min WI prior to PAS25 facilitated long-term potentiation (LTP)-like plasticity due to a homeostatic increase in cholinergic activity. |
| Databáze: | OpenAIRE |
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