Transfusion Practices in the Management of Sickle Cell Disease: A Survey of Florida Hematologists/Oncologists
| Autor: | Levette N. Dunbar, Donna R. Rivera, LaRae Coleman Brown, Abraham G. Hartzema, Richard Lottenberg |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Pediatrics Article Subject business.industry Mail survey Disease 030204 cardiovascular system & hematology 3. Good health 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Family medicine Educational resources Medicine Survey instrument Transfusion management business Research Article Clinical vignette |
| Zdroj: | ISRN Hematology |
| ISSN: | 2090-4428 2005-2006 |
| DOI: | 10.5402/2012/524513 |
| Popis: | The purpose of this study was to characterize transfusion practices in the management of sickle cell disease and to identify factors attributing to differences in prescribing practices among Florida hematologists/oncologists. A cross-sectional study was performed in 2005-2006 utilizing a mail survey. The survey instrument addressed practice characteristics, sickle cell patient populations, transfusion settings, indications and techniques, red blood cell phenotype specifications/modifications, use of practice guidelines, and educational resource utilization. One hundred fifty two physicians (75% adult-oriented, 25% pediatric) completed the survey. Non-academic practice settings (78 %) were the primary location. Pediatric practices had a larger percentage of patients with overt strokes, and receiving hydroxyurea therapy than adult-oriented practices. The majority of survey respondents did not request limited phenotypically matched red blood cells on a routine basis. The majority of pediatric practices (60%) had individually defined transfusion practice guidelines in contrast to 8% of adult-oriented practices. There were statistically significant differences for pediatric and adult-oriented practices in managing certain acute and chronic transfusion indications. Analysis of clinical vignette data revealed variation among hematologists/oncologists in the transfusion management of common clinical scenarios. The study underscores the need for the development and dissemination of comprehensive sickle cell transfusion guidelines and protocols. |
| Databáze: | OpenAIRE |
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