Varicella Pneumonia: Case Report and Review of a Potentially Lethal Complication of a Common Disease
Autor: | James Tse, Sajjad Ibrar, John T. Denny, Geza K. Kiss, Joyce A. Bonitz, Shaul Cohen, Zoe M Rocke, Scott J. Mellender, Valerie A McRae, Julia E. Denny, Christine H. Fratzola |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Epidemiology medicine.medical_treatment viruses 030106 microbiology Case Report medicine.disease_cause 03 medical and health sciences 0302 clinical medicine varicella CPAP lcsh:Pathology medicine radiography of varicella pneumonia complications of varicella 030212 general & internal medicine Safety Risk Reliability and Quality Varicella Zoster Infection lcsh:R5-920 Past medical history Chickenpox integumentary system business.industry Varicella zoster virus virus diseases Immunosuppression medicine.disease Pneumonia varicella pneumonia lcsh:Medicine (General) business Complication Safety Research lcsh:RB1-214 Shingles |
Zdroj: | Journal of Investigative Medicine High Impact Case Reports Journal of Investigative Medicine High Impact Case Reports, Vol 6 (2018) |
ISSN: | 2324-7096 |
Popis: | Varicella zoster virus causes varicella (chickenpox). It can be reactivated endogenously many years later to cause herpes zoster (shingles). Although varicella is usually a benign disease in healthy children, it resulted in over 11 000 hospitalizations and over 100 deaths every year, in all ages, in the United States. Morbidity was considerably worse in older teenagers and adults. Between 5% and 15% of cases of adult chickenpox will produce some form of pulmonary illness. Progression to pneumonia risk factors include pregnancy, age, smoking, chronic obstructive pulmonary disease, and immunosuppression. Typically, pulmonary symptoms occur 1 to 6 days after varicella zoster infection. They often include cough, fever, and dyspnea. Treatment is a 7-day course of intravenous acyclovir for varicella pneumonia. Early intervention may modify the course of this complication. This review illustrates practical features with a case of a 34-year-old female with severe varicella pneumonia. Despite the lack of significant past medical history and absence of immunosuppression, her pneumonia worsened and by using continuous positive airway pressure mask, intubation was avoided. More important, the radiographic progression of severe varicella pneumonia is shown. This highlights how a common disease of varicella can progress in an adult and manifest with significant organ malfunction. |
Databáze: | OpenAIRE |
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