Predictive factors of urinary retention following prostate brachytherapy
| Autor: | Sabeena Sidhu, Mira Keyes, Joseph Bucci, Veronika Moravan, Ingrid Spadinger, W. James Morris |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty medicine.medical_treatment Urinary system Brachytherapy Urology Urinary catheterization Prostate medicine Humans Radiology Nuclear Medicine and imaging Aged Univariate analysis Analysis of Variance Radiation Catheter insertion business.industry Urinary retention Prostatic Neoplasms Middle Aged Urinary Retention Surgery medicine.anatomical_structure Oncology Regression Analysis International Prostate Symptom Score medicine.symptom business Urinary Catheterization Prostate brachytherapy |
| Zdroj: | International journal of radiation oncology, biology, physics. 53(1) |
| ISSN: | 0360-3016 |
| Popis: | Purpose: To evaluate the incidence and duration of urinary retention requiring catheterization and the factors predictive for these end points. Methods and Materials: Two hundred eighty-two patients treated with prostate brachytherapy alone were evaluated. Clinical and treatment-related factors examined included: age, baseline International Prostate Symptom Score (IPSS), presence of comorbidity, planning ultrasound target volume (PUTV), postimplant prostate CT scan volume, the CT:PUTV ratio, number of seeds inserted, number of needles used, use of neoadjuvant hormones, procedural physician, clinical stage, Gleason score, and pretreatment PSA. Dosimetric quality indicators were also examined. Results: Urinary obstruction after prostate brachytherapy developed in 43 (15%) patients. The median duration of catheter insertion was 21 days (mean 49, range 1–365). Univariate analysis demonstrated that presence of diabetes, preimplant volume, postimplant volume, CT:PUTV ratio, number of needles, and dosimetric parameters were predictive for catheterization. However, in multivariate analysis, only the baseline IPSS, CT:PUTV ratio, and presence of diabetes were significant independent predictive factors for catheterization. Conclusion: Baseline IPSS was the most important predictive factor for postimplantation catheterization. The extent of postimplant edema, as reflected by the CT:PUTV ratio, predicted for need and duration of catheterization. The presence of diabetes was predictive for catheterization, but may relate to the absence of prophylactic steroids, and therefore requires further evaluation. |
| Databáze: | OpenAIRE |
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