Antibodies against some bacterial antigens in children
| Autor: | Sirkka Kontiainen, J. Mäenpää, TU Kosunen, I. Seppälä, M Verkasalo, Aaro Miettinen |
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| Rok vydání: | 1994 |
| Předmět: |
Bordetella pertussis
Adolescent Active immunization 03 medical and health sciences 0302 clinical medicine Seroepidemiologic Studies Prevalence Humans Medicine 030212 general & internal medicine Borrelia burgdorferi Child Finland Whooping cough biology business.industry Age Factors Infant Newborn Autoantibody Infant Bacterial Infections General Medicine Helicobacter pylori biology.organism_classification medicine.disease Antibodies Bacterial 3. Good health Child Preschool Population Surveillance Pediatrics Perinatology and Child Health Immunology biology.protein 030211 gastroenterology & hepatology Bacterial antigen Antibody business |
| Zdroj: | Acta Paediatrica. 83:1137-1142 |
| ISSN: | 0803-5253 |
| Popis: | The prevalence of bacterial antibodies was determined in 173 children aged 0-15 years. The prevalence of IgG Borrelia burgdorferi antibodies in titres > 500 in children less than 8 years of age was 6% while none of the older children had these antibodies in titres > 400. IgG Helicobacter pylori antibodies were detected only in children older than 6 years of age, with a prevalence of 6.5%, as were IgA H. pylori antibodies, with a prevalence of 3.7%. The prevalence of high-titre IgG Campylobacter jejuni antibodies was 1.2%, that of IgA 1.8% and IgM 1.2%. The prevalence of high-titre (> 500 IU/ml) antistreptolysin O was 3%, that of antistaphylolysin-alpha (> or = 4 IU/ml) 2% and that of anti-teichoic acid antibodies (titre 2) 2%. Low-titre Yersinia antibodies were detected in 2%. High-titre Bordetella pertussis antibodies were detected in 6% of recently vaccinated children and in 8% of children in their first years of school. In the latter, high-titre antibodies were mainly of the IgM and IgA classes. Altogether 35 children tested positive for bacterial antibodies other than Bordetella pertussis antibodies. Clinical evaluation revealed a possible infection, suggested by the antibody, in 5 (3%) of the children. Two (vaccinated) children had evidence of whooping cough. Eight of the 35 children with high-titre bacterial antibodies (23%) also had elevated levels of autoantibodies (but not autoimmune diseases). |
| Databáze: | OpenAIRE |
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