Marek's disease virus in vaccinated poultry flocks in Turkey: its first isolation with molecular characterization
| Autor: | Ismail Sahindokuyucu, Nilufer Kuruca, Mustafa Yavuz Gülbahar, Harun Albayrak, Gerald Barry, Efe Karaca, Zafer Yazici, Emre Ozan, Bahadir Muftuoglu, Cuneyt Tamer, Semra Gumusova, Ahmed Eisa Elhag, Sinem Inal, Hanne Nur Kurucay |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Turkey Virulence Biology Virus Poultry 03 medical and health sciences Medical microbiology Virology Geese medicine Marek Disease Animals Herpesvirus 2 Gallid Cells Cultured Phylogeny Poultry Diseases 030304 developmental biology 0303 health sciences Marek's disease Base Sequence 030306 microbiology business.industry Subclade General Medicine Poultry farming biology.organism_classification Vaccination Ducks Italy Flock Poland business Chickens |
| Zdroj: | Archives of virology. 166(2) |
| ISSN: | 1432-8798 |
| Popis: | Marek's disease (MD) is an important disease of avian species and a potential threat to the poultry industry worldwide. In this study, 16 dead commercial chickens from flocks with suspected MD were necropsied immediately after death. Pathological findings were compatible with MD, and gallid alphaherpesvirus 2 was identified in PCR of spleen samples. Virus isolation was performed in primary cell culture, and partial sequencing of the meq gene of the isolate revealed >99% nucleotide sequence identity to virulent and very virulent plus strains from a number of European countries, placing it in the same subclade of clade III as two virulent Italian strains and a very virulent plus Polish strain as well as virulent strains of geese and ducks. The data reported here indicate that a virulent strain of Marek's disease virus is circulating in Turkey and has not been stopped by the current national vaccination programme. |
| Databáze: | OpenAIRE |
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