Antimicrobial activity of isocytisoside and extracts of Aquilegia vulgaris L
| Autor: | M. Szaufer-Hajdrych, O Goślińska, I. MatłAwska, W. Bylka |
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| Rok vydání: | 2004 |
| Předmět: |
Nystatin
Antifungal Agents Gram-positive bacteria Aquilegia Flavonoid Ranunculaceae Microbial Sensitivity Tests medicine.disease_cause Gram-Positive Bacteria Applied Microbiology and Biotechnology Microbiology Glucosides Gram-Negative Bacteria medicine Food science chemistry.chemical_classification biology Plant Extracts Aspergillus niger Fungi biology.organism_classification Antimicrobial Isoflavones Anti-Bacterial Agents Plant Leaves chemistry Staphylococcus aureus Aquilegia vulgaris Gentamicins |
| Zdroj: | Letters in applied microbiology. 39(1) |
| ISSN: | 0266-8254 |
| Popis: | Aims: The aim of this study was to analyse the antimicrobial properties extracts of Aquilegia vulgaris, and their principial flavonoid component and to compare the obtained results with the activity of gentamicin and nystatin. Methods and Results: The ethanol, acetone and isopropanol extracts as well as the subextracts isolated from the methanol extract together with the main flavonoid: 4′-methoxy-5,7-dihydroxyflavone 6-C-glucoside (isocytisoside) were obtained from the leaves with stems of Aquilegia vulgaris L. All the extracts were analysed by TLC to confirm flavonoids and phenolic acids occurrence. The antimicrobial activity was tested by the method of series dilutions against different Gram-positive, Gram-negative bacteria and also fungi. The results have shown that the extracts, subextracts and isocytisoside inhibit growth of all studied micro-organisms, revealing the greatest activity against Gram-positive Staphylococcus aureus, Staph. epidermidis and the mould Aspergillus niger. Conclusions: The antimicrobial activity of the tested materials it is possibly related to the content of isocytisoside. Significance and Impact of the Study: This study has determined new activity of A. vulgaris and suggested the necessity of further studies. |
| Databáze: | OpenAIRE |
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