Femoral head penetration in Vitamin-E polyethylene liner versus conventional liners in total hip arthroplasty: systematic review and meta-analysis of randomised control trials
| Autor: | Himanshu Yadav, Mohamed Rabea, James A. Harty, Hany Elbardesy, Shane Guerin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
polyethylene
medicine.medical_treatment vitamin-e Dentistry Review Article head penetration Femoral head Medicine Orthopedics and Sports Medicine primary hip replacement radio stereometry Orthopedic surgery Hip business.industry Vitamin E Polyethylene liner meta-analysis medicine.anatomical_structure Systematic review Relative risk Meta-analysis Cohort Surgery business RD701-811 Total hip arthroplasty |
| Zdroj: | SICOT-J, Vol 7, p 47 (2021) SICOT-J |
| ISSN: | 2426-8887 |
| Popis: | Background: Debate encompasses the use of Vitamin E Polyethylene or conventional Polyethylene liner in primary hip arthroplasty. Does the Inclusion of Vitamin E in PE give adequate protection from oxidation and maintains lower rates of wear? Patients and methods: We performed this study following the Preferred Reporting Items for Systematic Reviews and Meta-analyses Statement (PRISMA) and the Cochrane Handbook for systematic reviews and meta-analysis. Studies were included from any region, written in any language. We had only the randomised control trials comparing the femoral head penetration between Vitamin-E diffused highly cross-linked polyethylene (VEPE) liner and conventional liners in primary total hip arthroplasty. Results: We included 10 studies in this meta-analysis. We conducted them using Review Manager V.5.0. We computed the risk ratio to measure the treatment effect, considering the heterogeneity. We used Random-effect models. VEPE had insignificant marginal advantages for FHP within three months post-operative. Additionally, VEPE showed significantly less FHP after two and five years. After one year, it showed significantly less FHP with the VEPE group versus the UHMWPE cohort and a non-significant difference between the VEPE and XLPE group. Conclusions: In terms of FHP, this metanalysis shows less FHP for the VEPE than conventional PE. A longer follow-up period is required to evaluate whether the oxidation protection gained by Vitamin E results in lower wear rates, less osteolysis, and aseptic loosening compared to the conventional PE in the long term. |
| Databáze: | OpenAIRE |
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