| Autor: |
Auvinen, P., Vehviläinen, J., Marjonen, H., Modhukur, V., Sokka, J., Wallén, E., Rämö, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H., Kaminen-Ahola, N. |
| Rok vydání: |
2023 |
| DOI: |
10.6084/m9.figshare.22613035.v1 |
| Popis: |
Additional file 2: Figure S1. Timing and amount of maternal alcohol consumption in categories Figure S2. Characterization of hESC differentiation into germ layer cells Figure S3. Q-Q plots of genome-wide DNAm (adjusted by smoking and sex) and sensitivity analyses (adjusted by sex, maternal age, mode of delivery, and parity) Figure S4. SVD plots of sensitivity analysis for candidate genes Figure S5. PCA for PAE-associated DMPs in placenta Figure S6. Effect sizes of candidate gene DMPs in genome-wide DNAm and sensitivity analyses Figure S7. Schematic figure about PAE-associated DMR at IGF2/H19 locus in placenta Figure S8. Cell-type composition in placental samples Figure S9. GWAM comparison between control and PAE placentas Figure S10. GWAM comparison between alcohol-exposed and control hESCs Figure S11. Pathway analysis of DMPs in hESCs Figure S12. Pathway analysis of DMRs in hESCs Figure S13. Pathway analysis of differentially expressed genes in hESCs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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