Sensitive periods in development of endometriosis
| Autor: | Vladislav S Baranov |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
endometriosis medicine.medical_specialty epigenetic drivers genome reprogramming lcsh:QH426-470 Mullerian Ducts Endometriosis Biochemistry 03 medical and health sciences 0302 clinical medicine Sensitive periods Genetics Medicine Epigenetics sensitive developmental periods Genetics (clinical) Ecology Evolution Behavior and Systematics Gynecology System development 030219 obstetrics & reproductive medicine Ecology business.industry Mesenchymal stem cell External endometriosis medicine.disease lcsh:Genetics 030104 developmental biology Stem cell genetic business |
| Zdroj: | Экологическая генетика, Vol 16, Iss 2, Pp 36-39 (2018) |
| ISSN: | 2411-9202 1811-0932 |
| Popis: | The hypothesis of three sensitive periods (SP) in development of common gynecological disease external endometriosis (EM) is suggested: I prenatal female genital system development from the stem cells (SC) of Mullerian ducts; II uterine endometrial cells transition into mesenchymal meSC; III endometriotic lesions implantation and growth within pelvic lining. Genetic and epigenetic drivers operative at each SP of EM are outlined and their implication for understanding EM origin and development are briefly discussed. |
| Databáze: | OpenAIRE |
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