Lung Ultrasound for the Diagnosis of Pneumonia in Children: A Meta-analysis
| Autor: | Catherine C. Hooper-Miele, Carrie Price, Mark C. Steinhoff, Laura E. Ellington, Margaret Gross, Robert H. Gilman, Miguel A. Chavez, James M. Tielsch, Maria Alejandra Pereda, William Checkley |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pediatrics Review Article Cochrane Library Sensitivity and Specificity Internal medicine medicine Humans Child Lung Ultrasonography Cause of death Evidence-Based Medicine Receiver operating characteristic business.industry Pneumonia medicine.disease United States Confidence interval Pulmonology Meta-analysis Pediatrics Perinatology and Child Health Guideline Adherence business Biomedical sciences |
| Zdroj: | Pediatrics |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2014-2833 |
| Popis: | BACKGROUND AND OBJECTIVE: Pneumonia is the leading cause of death of children. Diagnostic tools include chest radiography, but guidelines do not currently recommend the use of lung ultrasound (LUS) as a diagnostic method. We conducted a meta-analysis to summarize evidence on the diagnostic accuracy of LUS for childhood pneumonia. METHODS: We performed a systematic search in PubMed, Embase, the Cochrane Library, Scopus, Global Health, World Health Organization–Libraries, and Latin American and Caribbean Health Sciences Literature of studies comparing LUS diagnostic accuracy against a reference standard. We used a combination of controlled key words for age RESULTS: Five studies (63%) reported using highly skilled sonographers. Overall methodologic quality was high, but heterogeneity was observed across studies. LUS had a sensitivity of 96% (95% confidence interval [CI]: 94%–97%) and specificity of 93% (95% CI: 90%–96%), and positive and negative likelihood ratios were 15.3 (95% CI: 6.6–35.3) and 0.06 (95% CI: 0.03–0.11), respectively. The area under the receiver operating characteristic curve was 0.98. Limitations included the following: most studies included in our analysis had a low number of patients, and the number of eligible studies was also small. CONCLUSIONS: Current evidence supports LUS as an imaging alternative for the diagnosis of childhood pneumonia. Recommendations to train pediatricians on LUS for diagnosis of pneumonia may have important implications in different clinical settings. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|