Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
| Autor: | Harald Hausen, Ethel Michele De Villiers |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty business.industry indirect carcinogenesis medicine.medical_treatment Myeloid leukemia Type 2 Diabetes Mellitus Neoplasms. Tumors. Oncology. Including cancer and carcinogens Immunosuppression bovine meat and milk factors (BMMF) Review Type ii diabetes medicine.anatomical_structure Oncology Prostate Immunology Epidemiology medicine chronic zoonosis Cancer risk business Carcinogen RC254-282 |
| Zdroj: | Cancers Cancers, Vol 13, Iss 5407, p 5407 (2021) |
| ISSN: | 2072-6694 |
| Popis: | Simple Summary This manuscript emphasizes the mechanistic differences of infectious agents contributing to human cancers either by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens differs (e.g., response to immunosuppression) from those cancers linked with indirect infectious interactions. We discuss their role in colon, breast, and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF (bovine meat and milk factor) infections in acute myeloid leukemia. Abstract Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to immunosuppression) differs from those cancers linked with indirect infectious interactions. Cancers induced by direct infectious carcinogens commonly increase under immunosuppression, whereas the cancer risk by indirect carcinogens is reduced. This influences their responses to preventive and therapeutic interferences. In addition, we discuss their role in colon, breast and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF infections in acute myeloid leukemia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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