Intestinal epithelium integrity after delayed onset of nutrition in broiler chickens
| Autor: | J. van Baal, G. de Vries Reilingh, Aart Lammers, S. de Vries, Bas Kemp, M.S. Hollemans |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pore size
Time Factors animal structures Animal Nutrition tight junction Nutritional Status Ileum Biology broiler digestive system Metabolism and Nutrition Tight Junctions Feeding Methods 03 medical and health sciences Animal science delayed nutrition Blood plasma medicine Animals Animal Husbandry Intestinal Mucosa Adaptatiefysiologie 030304 developmental biology lcsh:SF1-1100 intestinal integrity 0303 health sciences Intestinal permeability digestive oral and skin physiology 0402 animal and dairy science Broiler Delayed onset 04 agricultural and veterinary sciences General Medicine medicine.disease Animal Feed 040201 dairy & animal science Intestinal epithelium Diervoeding Diet medicine.anatomical_structure Paracellular transport WIAS gene expression Adaptation Physiology Animal Science and Zoology lcsh:Animal culture Chickens |
| Zdroj: | Poultry Science, 99(12), 6818-6827 Poultry Science 99 (2020) 12 Poultry Science, Vol 99, Iss 12, Pp 6818-6827 (2020) Poultry Science |
| ISSN: | 0032-5791 6818-6827 |
| DOI: | 10.1016/j.psj.2020.08.079 |
| Popis: | Fasting older broiler chickens (>7 d of age) enlarges the intestinal tight junction (TJ) pore size, resulting in high paracellular intestinal permeability. Broiler chickens often do not receive feed and water (nutrition) directly after hatch, which may result in fasting up to 72 h of age. Whether perinatal fasting affects intestinal permeability is minimally studied. We therefore investigated whether delayed access to nutrition after hatch increases intestinal permeability, compared with broilers receiving early access to nutrition. Therefore, 432 hatched broilers received nutrition 72 h after hatch (delayed nutrition [DN]) or directly after hatch (early nutrition [EN]) and were reared under similar conditions until 14 d of age. Two hours after application of an oral pulse dose (3.85 mg) of fluorescein isothiocyanate-dextran (4000 Da) at 4, 10, and 14 d of age, blood plasma concentrations of the marker were measured in 24 to 36 broilers per treatment and time point. Marker concentration in plasma did not differ between DN and EN broilers at any age. The villus width measured in at least 8 broilers per treatment was smaller in DN than in EN broilers at 4 d for both the ileum (92 ± 3 μm vs. 121 ± 4; P |
| Databáze: | OpenAIRE |
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