FIVE MICRO‐CURIE UREA BREATH TEST FOR THE DIAGNOSIS OFHELICOBACTER PYLORIINFECTION: EVALUATION IN A SOUTH‐EAST ASIAN POPULATION
| Autor: | E. H. Ng, Soo Yong Tan, Pierce K. H. Chow, S. E. Aw, W. K. Yu, A. S. W. Goh, Khee Chee Soo |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Peptic Ulcer medicine.medical_specialty Helicobacter pylori infection Urea breath test Population Sensitivity and Specificity Gastroenterology Helicobacter Infections Double-Blind Method Predictive Value of Tests Internal medicine medicine Humans Urea South east asian education Asia Southeastern Aged Aged 80 and over Breath test education.field_of_study Helicobacter pylori biology medicine.diagnostic_test business.industry General Medicine Gold standard (test) Middle Aged biology.organism_classification Breath Tests Predictive value of tests Female Surgery business |
| Zdroj: | Australian and New Zealand Journal of Surgery. 69:37-40 |
| ISSN: | 1445-2197 0004-8682 |
| Popis: | Background: Helicobacter pylori is an important pathogen responsible for significant morbidity and mortality. Its prevalence varies widely in different geographical locations and is especially high in parts of Asia. Methods: A double-blind study was carried out to evaluate the use of the 5 μCi (185 KBq) [14C]-urea breath test ([14C]-UBT) in a South-East Asian population by validating its diagnostic accuracy against histology and the CLO test. Results: The sensitivity and specificity of the [14C]-UBT was 100% when compared against the CLO test. When histology was used as the ‘gold standard’, the sensitivity and specificity were 100% and 97.2%, respectively. There was no overlap or indeterminate values between positive and negative results on the [14C]-UBT. Conclusions: Among South-East Asian populations where the prevalence of H. pylori infection is high, the high sensitivity of the 5 μCi [14C]-UBT makes it a very important test in the detection of H. pylori. |
| Databáze: | OpenAIRE |
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