Effectiveness of opioid rotation in the control of cancer pain: The ROTODOL Study
| Autor: | Alentorn Xg, Jesús González-Barboteo, Martín Fj, Manuel Fa, Eito Ma, Candel Va, Sánchez-Magro I, Álvarez Mn, Porta-Sales J |
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| Přispěvatelé: | Universitat de Vic. Càtedra de Cures Pal·liatives |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Time Factors Severity of Illness Index Drug Administration Schedule Tertiary Care Centers Basal (phylogenetics) Analgèsics Rating scale Opioid rotation Neoplasms Humans Medicine Outpatient clinic Pharmacology (medical) Prospective Studies Adverse effect Aged Pain Measurement Aged 80 and over Drug Substitution business.industry Breakthrough Pain General Medicine Middle Aged Intensity (physics) Analgesics Opioid Treatment Outcome Anesthesiology and Pain Medicine Opioid Spain Anesthesia Female Chronic Pain Opi Dolor oncològic business Cancer pain medicine.drug |
| Zdroj: | RIUVic. Repositorio Institucional de la Universidad de Vic instname |
| ISSN: | 1551-7489 |
| DOI: | 10.5055/jom.2014.0236 |
| Popis: | Objective: To assess the effectiveness of opioid rotation (OR) to manage cancer pain. To describe the adverse events (AEs) associated with OR. Setting: Thirty-nine tertiary hospital services.Patients: Sixty-seven oncological patients with cancer-related pain treated at outpatient clinics.Intervention: Prospective multicenter study. Pain intensity was scored using a Numerical Rating Scale (NRS) of 0-10. Average pain (AP) intensity in the last 24 hours, breakthrough pain (BTP), and the number of episodes of BTP on the days before and 1 week after OR were assessed. The pre-OR and post-OR opioid were recorded. The presence and intensity of any AEs occurring after OR were also recorded.Results: In the 67 patients evaluated, 75 ORs were recorded. In all cases, the main reason for OR was poor pain control. Pain intensity decreased by ≥2 points after OR in 75.4 percent and 57.8 percent of cases for AP and BTP, respectively. If the initial NRS score was ≥4, a decrease below |
| Databáze: | OpenAIRE |
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