Does auxiliary heterotopic liver transplantation reverse hypersplenism and portal hypertension?
| Autor: | Solko W. Schalm, Sjoerd de Rave, Inne H.M. Borel Rinkes, H M Zonderland, Arthur Gerritsen Van Der Hoop, Herold J. Metselaar, Onno T. Terpstra, E. J. Hesselink |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Transplantation Heterotopic Orthotopic liver transplantation medicine.medical_treatment Antithrombin III Liver transplantation Leukocyte Counts Chronic liver disease Gastroenterology Hypersplenism Leukocyte Count Internal medicine Hypertension Portal medicine Humans Platelet Serum Albumin Hepatology Platelet Count business.industry Ascites Bilirubin Middle Aged medicine.disease Liver Transplantation Surgery Transplantation Portal hypertension Female business |
| Zdroj: | Gastroenterology. 100:1126-1128 |
| ISSN: | 0016-5085 |
| DOI: | 10.1016/0016-5085(91)90293-t |
| Popis: | In this study, performed to assess the effect of auxiliary heterotopic liver transplantation on portal hypertension and hypersplenism, eight patients with chronic liver disease who underwent the procedure and had functioning grafts for at least 6 months were analyzed. The transplantation resulted in (a) normalization of platelet and leukocyte counts, (b) reduction of splenomegaly by 20% +/- 3% (P less than 0.02), (c) disappearance of ascites, and (d) diminution of esophageal varices in all patients. Intraoperatively, the mean portacaval pressure gradient decreased with 54% +/- 7% after recirculation of the graft (P less than 0.05). In conclusion, a functioning auxiliary heterotopic liver graft decompresses portal hypertension and reverses hypersplenism. |
| Databáze: | OpenAIRE |
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