Myocardial infarction and oral contraceptive agents
Autor: | Bernard L. Segal, Hans Van Den Broek, Demetrios Kimbiris, William Likoff, Edward B. Waxler |
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Rok vydání: | 1971 |
Předmět: |
Adult
medicine.medical_specialty Chlormadinone Acetate Arteriosclerosis medicine.drug_class Population Myocardial Infarction Infarction Coronary Angiography Ethinyl Estradiol chemistry.chemical_compound Internal medicine medicine Humans Myocardial infarction education Blood Coagulation education.field_of_study Dimethisterone business.industry Obstetrics and Gynecology Mestranol General Medicine medicine.disease Thrombosis Embolism chemistry Estrogen Cardiology Female Norethindrone Cardiology and Cardiovascular Medicine business Contraceptives Oral medicine.drug |
Zdroj: | The American Journal of Cardiology. 28:96-101 |
ISSN: | 0002-9149 |
Popis: | Three young premenopausal women, aged 27, 29 and 35 years, with acute myocardial infarction in the absence of significant predisposing causes are presented. All 3 patients were taking oral contraceptive agents at the time of infarction. Selective coronary arteriograms showed an isolated segmental occlusion in all cases with no other arterial disease. Although these events must be considered rare, oral contraceptive agents may be a possible contributing factor in myocardial infarction by a mechanism of thrombosis. The role of estrogens in myocardial infarction and atherosclerosis is reviewed. The implication of these cases for increased incidence of thromboembolic disorders in clinical trials of estrogen in atherosclerotic disease is discussed. |
Databáze: | OpenAIRE |
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