Hyponatraemia as a Predictor of Mortality in Medical Admissions in Ghana: A Comparative Study

Autor:	Abena Yeboaa Tannor, Martin Agyei, Elliot Koranteng Tannor, Emmanuel Owusu Akumiah, Yasmin Adoma Boateng, Afua Ofori
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	medicine.medical_specialty Article Subject business.industry ELECTROLYTE ABNORMALITY Mortality rate Logistic regression Diseases of the genitourinary system. Urology Teaching hospital Continuous variable Nephrology Internal medicine Medicine In patient RC870-923 Medical diagnosis business Low serum albumin Research Article
Zdroj:	International Journal of Nephrology, Vol 2020 (2020) International Journal of Nephrology
ISSN:	2090-2158
Popis:	Background. Hyponatraemia is the most common electrolyte abnormality in hospital admissions. It occurs in a quarter of medical admissions in Ghana, and it is associated with high mortality. Mortality has been suggested to be due to the underlying medical condition and not necessarily the hyponatraemia. We set out to compare the outcomes of patients with documented hyponatraemia as compared to those with normonatraemia in terms of mortality and length of hospital stay. Methods. We conducted a comparative analysis of patients with hyponatraemia and those with normonatraemia on the medical ward at the Komfo Anokye Teaching Hospital between May 2018 and December 2018. The medical diagnoses, demographics, and laboratory data of the patients were recorded. Participants’ age and gender were matched. Student’s t-test was used to test for differences in continuous variables when parametric and Wilcoxon signed-rank test for nonparametric variables. Multiple logistic regression was used to identify predictors of in-hospital mortality. Apvalue of p=0.002). In-hospital stay was longer in patients with hyponatraemia than normonatraemia (7 (4–10) vs. 6 (3–10) days) but not statistically significantp=0.09. Multiple logistic regression showed that low serum sodiump<0.001and low serum albuminp=0.009were the predictors of in-hospital mortality. Conclusion. Hyponatraemia is associated with significantly higher mortality than normonatraemia and predicts worse prognosis in patients on medical admission. Low serum albumin is also a predictor of mortality in medical admission.
Databáze:	OpenAIRE
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