Prevalence of the M Protein Gene in Group C and Group G Streptococci Isolated from Patients in Thailand
| Autor: | Suwandee Sapcharoen, Perapon Nitayanon, Chanwit Tribuddharat, Somporn Srifuengfung |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) Cefotaxime Adolescent Genotype Tetracycline 030106 microbiology Erythromycin Microbial Sensitivity Tests Bioinformatics Polymerase Chain Reaction Group A Microbiology Young Adult 03 medical and health sciences chemistry.chemical_compound Streptococcal Infections Prevalence medicine Humans Child Aged Aged 80 and over Antigens Bacterial business.industry Chloramphenicol Streptococcus Clindamycin Sequence Analysis DNA General Medicine Middle Aged Thailand Anti-Bacterial Agents Penicillin stomatognathic diseases 030104 developmental biology Infectious Diseases chemistry Child Preschool Linezolid Female Carrier Proteins business Bacterial Outer Membrane Proteins medicine.drug |
| Zdroj: | Japanese Journal of Infectious Diseases. 70:108-110 |
| ISSN: | 1884-2836 1344-6304 |
| DOI: | 10.7883/yoken.jjid.2015.616 |
| Popis: | We surveyed group C and group G β-hemolytic streptococci for emm and emmL (emm -like) genes which encode the M protein, as well as determined their antimicrobial susceptibilities. A total of 97 isolates 79 GCS/GGS isolates and 18 isolates from other groups were tested for the M protein gene by PCR. Focusing on invasive infections with group A (GAS), group C (GCS), and group G (GGS) β-hemolytic streptococci isolated from blood, the M protein gene was found in 90.0%, 84.6%, and 78.3% of isolates, respectively. The hypervariable N terminal region of the emm was sequenced from 62 isolates, and 26 types of the emm gene were identified. Based on these results, type emm222.2 may be endemic to Thailand. The results of antimicrobial susceptibility testing of groups C, G, and non-groups A to G isolates indicated high susceptibility (range 82-100%) to penicillin, cefotaxime, chloramphenicol, clindamycin, erythromycin, linezolid, ofloxacin, and vancomycin, whereas the isolates showed low susceptibility (range 0-15.6%) to tetracycline. |
| Databáze: | OpenAIRE |
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