Prevalence of Components of Metabolic Syndrome Among Adults with the Presence of Autoimmune Thyroid Condition in an Iodine-Sufficient Region
Autor: | Hang Zhou, Qin Zhang, Binyu Pan, Zheng Feei Ma |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male China endocrine system endocrine system diseases Endocrinology Diabetes and Metabolism Clinical Biochemistry Thyroid Gland Thyrotropin Physiology 010501 environmental sciences 01 natural sciences Biochemistry Inorganic Chemistry 03 medical and health sciences chemistry.chemical_compound Diabetes mellitus Prevalence medicine Humans Hyperuricemia 0105 earth and related environmental sciences Metabolic Syndrome 0303 health sciences medicine.diagnostic_test business.industry 030302 biochemistry & molecular biology Biochemistry (medical) Hypertriglyceridemia Thyroid General Medicine medicine.disease Anti-thyroid autoantibodies medicine.anatomical_structure chemistry Uric acid Female Metabolic syndrome business Lipid profile Iodine |
Zdroj: | Biological Trace Element Research. 199:2837-2843 |
ISSN: | 1559-0720 0163-4984 |
DOI: | 10.1007/s12011-020-02413-3 |
Popis: | The presence of autoimmune thyroid condition could lead to thyroid dysfunction in adults. In addition, thyroid antibody positivity has been suggested to be associated with hyperuricemia, diabetes and obesity in individuals with thyroid autoimmune diseases. Currently, there are limited studies that assessed the relationship of thyroid antibody with the components of metabolic syndrome in adults, especially from iodine-sufficient regions. Therefore, the aim of this study was to determine the prevalence of components of metabolic syndrome in Chinese adults with autoimmune thyroid condition. Medical records of adult inpatients in the Suzhou Ninth People's Hospital, Suzhou, Jiangsu, China, from January 2016 to September 2019 were reviewed and included after screening for eligibility. A total of 1105 participants were included in our final analysis, and of these, 77.5% (n = 856) were females. There was a higher prevalence of thyroid antibodies in females than males (30.6% vs. 23.7%) (p = 0.034). Although there were significant differences in mean TSH, FT3 and FT4 values between participants positive and negative for thyroid antibodies, these values were still within the normal reference range. No differences in the mean BMI, prevalence of diabetes, hyperuricemia, hypertriglyceridemia and hypercholesterolemia between participants positive and negative for thyroid antibodies were reported (p > 0.05). In conclusion, our study reported that participants positive for thyroid antibodies did not appear to be accompanied by abnormal thyroid function, lipid profile, uric acid and glucose concentrations. |
Databáze: | OpenAIRE |
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