Comparison of functional and oncological outcomes of innovative 'three-port' and traditional 'four-port' laparoscopic radical prostatectomy in patients with prostate cancer
| Autor: | Qian Zhang, Si-da Cheng, Yi-Ji Peng, Ben Xu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Biochemical recurrence
Male medicine.medical_specialty Laparoscopic radical prostatectomy Urology medicine.medical_treatment 030232 urology & nephrology lcsh:RC870-923 Group B 03 medical and health sciences Prostate cancer 0302 clinical medicine Port (medical) Continence Medicine Humans In patient Aged Retrospective Studies Prostatectomy business.industry Prostatic Neoplasms General Medicine Middle Aged medicine.disease lcsh:Diseases of the genitourinary system. Urology Prostate-specific antigen Oncological control Treatment Outcome Reproductive Medicine 030220 oncology & carcinogenesis lipids (amino acids peptides and proteins) Laparoscopy Positive Surgical Margin business Three-port Research Article |
| Zdroj: | BMC Urology BMC Urology, Vol 21, Iss 1, Pp 1-6 (2021) |
| ISSN: | 1471-2490 |
| Popis: | Background To compare the functional and oncological outcomes between innovative “three-port” and traditional “four-port” laparoscopic radical prostatectomy (LRP) in patients with prostate cancer (PCa). Methods We retrospectively collected the data of PCa patients treated at our institutions from June 2012 to May 2016. According to the inclusion criteria, a total of 234 patients were included in the study, including 112 in group A (four-port) and 122 in group B (three-port). The perioperatively surgical characteristics, functional and oncological outcomes were compared between groups. Results There were no statistical differences in the baseline parameters between these two groups. Compared with group A, the operative time (OT) and estimated blood loss (EBL) were significantly less in group B. On follow-up, the rate of positive surgical margin (PSM), prostate specific antigen (PSA) biochemical recurrence and continence after LRP did not show any statistically significant difference between the groups. An identical conclusion was also received in comparison of overall survival (OS) and biochemical recurrence-free survival (BRFS) between both groups. Conclusions Innovative “three-port” LRP can significantly shorten the OT and reduce the EBL compared with the traditional “four-port” LRP. Meanwhile, it does not increase the rate of PSM and PSA biochemical recurrence. “Three-port” LRP could be popularized in the future in view of its superior surgical technique, considerably better functional outcomes and remarkable oncological control. |
| Databáze: | OpenAIRE |
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