Wegener's granulomatosis
| Autor: | Nelson R. Niles, Gordon L. Maurice, John E. Tuhy |
|---|---|
| Rok vydání: | 1958 |
| Předmět: |
030203 arthritis & rheumatology
Pathology medicine.medical_specialty Lung Tuberculosis Granuloma Polyarteritis nodosa business.industry Granulomatosis with Polyangiitis Autopsy General Medicine medicine.disease Focal Glomerulonephritis Medical Records 3. Good health Polyarteritis Nodosa 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Necrotizing Vasculitis medicine Arteritis Complication business 030217 neurology & neurosurgery |
| Zdroj: | The American journal of medicine. 25(4) |
| ISSN: | 0002-9343 |
| Popis: | Wegener's granulomatosis is characterized by necrotizing granulomatous lesions of the upper respiratory tract and/or lungs, necrotizing vasculitis and focal glomerulonephritis, terminating usually in uremia. Two additional cases are reported, bringing the total in the literature to thirty-seven. In Case I an initial erroneous diagnosis of tuberculosis was made histopathologically from the resected segment of lung and from autopsy material. Death was due to spontaneous subarachnoid hemorrhage complicating arteritis. This complication, and the cerebral lesions found at autopsy in Case II, have not hitherto been reported in this disease. The spectrum formed by this and other conditions closely related to polyarteritis nodosa is discussed. A hypersensitivity mechanism has been inferred by most authors but its nature remains to be elucidated. Treatment of this disease so far has been unsatisfactory. |
| Databáze: | OpenAIRE |
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