Successful pancreas transplantation alone is associated with excellent self-identified health score and glucose control: A retrospective study from a high-volume center in the United States
| Autor: | Stephen T. Bartlett, Joseph R. Scalea, Blythe Fiscella, Niket Todi, Allison Piedmonte, Jastine Paran, Lauren Pettinato, Amanda Bartosic, Eric Siskind |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Glucose control Health Status medicine.medical_treatment 030232 urology & nephrology Blood sugar 030230 surgery Pancreas transplantation Hypoglycemia Article Young Adult 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine Humans Medicine Transplantation business.industry Insulin Graft Survival Retrospective cohort study Middle Aged Prognosis medicine.disease Glucose medicine.anatomical_structure Hyperglycemia Quality of Life Female Pancreas Transplantation business Pancreas Hospitals High-Volume Follow-Up Studies |
| Zdroj: | Clinical Transplantation. 32:e13177 |
| ISSN: | 0902-0063 |
| DOI: | 10.1111/ctr.13177 |
| Popis: | BACKGROUND The benefits of pancreas transplantation are often difficult to measure. Here, we sought to determine the difference in quality of life for diabetic patients with and without a functional pancreas transplant alone (PTA). METHODS Pancreas transplant alone cases from 1993 to 2015 were considered. An IRB-approved survey inclusive of 15 questions spanning four domains was employed. Chi-square, Fisher's exact, and the T test were used where appropriate. RESULTS A total of 137 PTAs were performed during the study period. Of those reached (n = 32), 94% responded to the survey. Self-reported health scores were better (2.1 vs 3.0) for those with functioning pancreata (n = 18) vs those with a non-functional pancreas (n = 14), respectively (P = .036). Those with a functional pancreas had a HgbA1c of 5.3, vs 7.7 for a non-functional pancreas (P = .016). Significant hypoglycemia was reported in two of 18 with a functional transplant vs nine of 14 patients with a failed transplant (P = .003). Daily frustration with blood sugar affecting quality of life was significantly higher for patients with non-functional pancreas grafts (P |
| Databáze: | OpenAIRE |
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