Group II introns: structure, folding and splicing mechanism

Autor:	Olga Fedorova, Nora Zingler
Rok vydání:	2007
Předmět:	Genetics biology RNA Splicing Clinical Biochemistry Ribozyme Intron Proteins RNA Retrotransposon Bacterial genome size Group II intron Biochemistry Introns Evolutionary biology RNA splicing biology.protein Animals Nucleic Acid Conformation Group I catalytic intron Molecular Biology Protein Binding
Zdroj:	bchm. 388:665-678
ISSN:	1437-4315 1431-6730
DOI:	10.1515/bc.2007.090
Popis:	Group II introns are large autocatalytic RNAs found in organellar genomes of plants and lower eukaryotes, as well as in some bacterial genomes. Interestingly, these ribozymes share characteristic traits with both spliceosomal introns and non-LTR retrotransposons and may have a common evolutionary ancestor. Furthermore, group II intron features such as structure, folding and catalytic mechanism differ considerably from those of other large ribozymes, making group II introns an attractive model system to gain novel insights into RNA biology and biochemistry. This review explores recent advances in the structural and mechanistic characterization of group II intron architecture and self-splicing.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2fe3bcd17d37175c68daefd2c3cd62 https://doi.org/10.1515/bc.2007.090 Zobrazit plný text záznamu