Autor: |
Donoghue, Lauren J., McFadden, Kathryn M., Vargas, Daniel, Smith, Gregory J., Immormino, Robert M., Moran, Timothy P., Kelada, Samir N. P. |
Rok vydání: |
2023 |
DOI: |
10.6084/m9.figshare.23488817.v1 |
Popis: |
Additional file 2: Figures S1-S3. Figure S1. A BAL differential cell type percentages in HDM-exposed BALB/cJ and CC mice. Significance of t-test between eosinophil percentage between BALB/cJ and CC strains denoted as * for P < 0.01. B BAL differential cell counts for data shown in main text Figure 1B. Significance of t-tests of total cell counts and eosinophils between HDM-exposed BALB/cJ and CC011 mice are denoted by # for P < 0.1. Note BAL was performed on right lung lobes only. Figure S2. Perivascular inflammation and vascular remodeling in CC011 mice chronically exposed to HDM. Representative cross-sections of H&E stained lung tissue from CC011 mice exposed to PBS or HDM for 5 weeks. Tissue from HDM-exposed mice was collected immediately upon death due to repeated allergen exposure. Scale bars = 100uM. Figure S3. Median fluorescence intensity of IL-5 and IL-13 in ILC2s from BALB/cJ or CC011 mice, as determined by flow cytometry, following three treatments with PBS or HDM. Significance of t-tests for treatment effects within strain are denoted by * for P < 0.05. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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