Successful control of 2 simultaneous outbreaks of OXA-48 carbapenemase-producing Enterobacteriaceae and multidrug-resistant Acinetobacter baumannii in an intensive care unit

Autor: V. Pérez-Blanco, G. Ruiz Carrascoso, D. Abad Martín, J.C. Figueira Iglesias, M.A. Espinel Ruiz, Ana Robustillo-Rodela
Rok vydání: 2017
Předmět:
0301 basic medicine
Acinetobacter baumannii
Adult
Male
medicine.medical_specialty
Adolescent
Epidemiology
media_common.quotation_subject
030106 microbiology
030501 epidemiology
law.invention
Disease Outbreaks
03 medical and health sciences
law
Hygiene
Drug Resistance
Multiple
Bacterial
medicine
Humans
Cumulative incidence
Intensive care medicine
Decontamination
media_common
Aged
Cross Infection
Infection Control
biology
business.industry
Health Policy
Chlorhexidine
Public Health
Environmental and Occupational Health
Enterobacteriaceae Infections
Outbreak
Hydrogen Peroxide
Acinetobacter
Middle Aged
biology.organism_classification
Intensive care unit
Intensive Care Units
Infectious Diseases
Carbapenem-Resistant Enterobacteriaceae
Emergency medicine
Vaporized hydrogen peroxide
Female
Volatilization
0305 other medical science
business
medicine.drug
Acinetobacter Infections
Zdroj: American journal of infection control. 45(12)
ISSN: 1527-3296
Popis: This report describes a double outbreak of OXA-48-producing Enterobacteriaceae (OXA-48-PE) and multidrug-resistant Acinetobacter baumannii (MRAB) in an intensive care unit (ICU) and the effectiveness of measures implemented, including decontamination with vaporized hydrogen peroxide (VHP).Affected patients were isolated in a confined area and cared for by dedicated personnel. Four percent chlorhexidine soap was used for patient daily hygiene. All patients are subjected to contact precautions. An in-depth cleaning of the ICU was performed with a chlorine solution, followed by decontamination with VHP. Environmental samples were taken before and after the decontamination.From July-October 2015, 13 patients were colonized or infected by OXA-48-PE and 18 by MRAB in the ICU. The cumulative incidence of OXA-48-PE and MRAB was 3.48% and 4.81%, respectively. In the period after the intervention, they were 0.8% and 0%, respectively (P .001). Before the VHP biodecontamination, 4.5% of environmental samples were positive for OXA-48-PE and none for MRAB. After biodecontamination, 1.4% of samples were positive for OXA-48-PE.This study emphasizes the importance of environmental hygiene in the control of outbreaks caused by microorganisms of high environmental impact. The rapid effect after the VHP treatment suggests an influence of this measure in eradication.
Databáze: OpenAIRE
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