Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity
| Autor: | Edison Luiz Durigon, Marcílio Jorge Fumagalli, Gustavo Olszanski Acrani, Tristan P.W. Dennis, Jansen de Araujo, Márcio Roberto Teixeira Nunes, Robert J. Gifford, Luiz Carlos Vieira, Adriano de Oliveira Torres Carrasco, Luiz Tadeu Moraes Figueiredo, William Marciel de Souza, Gilberto Sabino Santos Jr, Marilia Farignoli Romeiro, Sejal Modha, Tatiana Ometto, Luzia Helena Queiroz, Felipe Gonçalves Motta Maia |
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| Rok vydání: | 2018 |
| Předmět: |
Whole genome sequencing
Parvovirus / patogenicidade biology Parvovirus business.industry viruses Genoma Viral / gen?tica media_common.quotation_subject virus diseases Infec??es por Parvoviridae / veterin?ria Distribution (economics) biology.organism_classification Evolutionary biology ZOONOSES POR VÍRUS Animais Dom?sticos / virologia business Animais Selvagens / virologia Diversity (politics) media_common |
| Zdroj: | Repositório Digital do Instituto Evandro Chagas (Patuá) Instituto Evandro Chagas (IEC) instacron:IEC Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | This work was supported by the Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo, Brazil (Grant number. 13/14929-1, and Scholarships No. 17/13981-0; 12/24150-9; 15/05778-5; 16/01414-1; 14/20851-8; 06/00572-0; 08/06411-4; 11/06810-9; 11/22663-6; 16/02568-2, 06/00572-0; 09/05994-9 and 11/13821-7). RJG was supported by the Medical Research Council of the United Kingdom (Grant number MC_UU_12014/10). University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. MRC-University of Glasgow Centre for Virus Research. Glasgow, United Kingdom. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. University of S?o Paulo. Institute of Biomedical Sciences. S?o Paulo, SP, Brazil. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil / University of S?o Paulo. Institute of Biomedical Sciences. S?o Paulo, SP, Brazil. Universidade Federal da Fronteira Sul. Passo Fundo, RS, Brazil. Universidade do Centro Oeste do Paran?. Guarapuava, PR, Brazil. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. MRC-University of Glasgow Centre for Virus Research. Glasgow, United Kingdom. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. University of S?o Paulo. Institute of Biomedical Sciences. S?o Paulo, SP, Brazil. S?o Paulo State University. Faculty of Veterinary Medicine. Ara?atuba, SP, Brazil. University of S?o Paulo. Institute of Biomedical Sciences. S?o Paulo, SP, Brazil. Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil. University of S?o Paulo. Ribeir?o Preto Medical School. Virology Research Center. Ribeir?o Preto, SP, Brazil. MRC-University of Glasgow Centre for Virus Research. Glasgow, United Kingdom. Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and domestic animals in Brazil. We identified 21 parvovirus sequences (including twelve nearly complete genomes and nine partial genomes) in samples derived from rodents, bats, opossums, birds and cattle in Pernambuco, S?o Paulo, Paran? and Rio Grande do Sul states. These sequences were investigated using phylogenetic and distance-based approaches, and were thereby classified into eight parvovirus species (six of which have not been described previously), representing six distinct genera in the subfamily Parvovirinae. Our findings extend the known biogeographic range of previously characterized parvovirus species, and the known host range of three parvovirus genera (Dependovirus, Aveparvovirus, and Tetraparvovirus). Moreover, our investigation provides a window into the ecological dynamics of parvovirus infections in vertebrates, revealing that many parvovirus genera contain well-defined sub-lineages that circulate widely throughout the world within particular taxonomic groups of hosts. |
| Databáze: | OpenAIRE |
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