STUDIES ON THE RESPIRATORY SYSTEM OF ASPERGILLUS ORYZAE V. SOME PROPERTIES OF THE RESPIRATORY SYSTEM OF MITOCHONDRIA FROM MYCELIA GROWN IN THE PRESENCE OF CHLORAMPHENICOL
| Autor: | Yasuyuki Ogura, Sakura Saito-Wakiyama |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Aspergillus oryzae
Cyanide Antimycin A Cytochrome c Group Mitochondrion Oxidative Phosphorylation General Biochemistry Genetics and Molecular Biology Pigment chemistry.chemical_compound Oxygen Consumption medicine Respiratory system Carbon Monoxide Growth medium Binding Sites Cyanides Dose-Response Relationship Drug biology Chemistry Chloramphenicol Pigments Biological biology.organism_classification Culture Media Mitochondria Citric acid cycle Aspergillus Biochemistry visual_art visual_art.visual_art_medium medicine.drug |
| Zdroj: | Japanese Journal of Medical Science and Biology. 30:125-135 |
| ISSN: | 1884-2828 0021-5112 |
| DOI: | 10.7883/yoken1952.30.125 |
| Popis: | Presence of chloramphenicol in the growth medium for mycelia of Aspergillus oryzae was without effect on the oxidative activity, respiratory control, or P/O ratio of isolated mitochondria. The mitochondria oxidized Krebs cycle intermediates even in the presence of cyanide at the concentration markedly inhibiting the normal mitochondrial oxidation. However, the P/O ratio during the mitochondrial oxidation decreased by about 1.0 on addition of cyanide. The c-type cytochromes, shown to occur in large amounts than in normal mitochondria (Wakiyama and Ogura, 1972), were suggested to act as electron carriers in this cyanide-resistant oxidation. A novel pigment, demonstrated only in the mitochondria prepared from chloramphenicol-treated mycelia by a CO-difference spectrum, was presumed to be the terminal oxidase of the respiration in the presence of cyanide. |
| Databáze: | OpenAIRE |
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