Body weight regulation of a low molecular weight xanthan gum on normal mice via gut microbiota
| Autor: | Bai Yanhong, Xincheng Sun, Qi Sun, Xuyang Hu, Zichao Wang, Zhang Jingnan, Jinqiang Hu, Suyue Xu, Chengxin Zhao, XiaYing Li, Xiaogen Zhang |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
chemistry.chemical_classification
Nutrition and Dietetics biology Nutrition. Foods and food supply Firmicutes Medicine (miscellaneous) Bacteroidetes Gut microbiota Butyrate Low molecular weight Gut flora Oligosaccharide biology.organism_classification Body weight chemistry Body weight regulation Propionate medicine TX341-641 Food science Xanthan gum Food Science medicine.drug |
| Zdroj: | Journal of Functional Foods, Vol 88, Iss, Pp 104874-(2022) |
| ISSN: | 1756-4646 |
| DOI: | 10.1016/j.jff.2021.104874 |
| Popis: | Properties of thickening, emulsification and suspension make xanthan gum is widely used in foods and other industries, but effects of xanthan oligosaccharide or low molecular weight xanthan gum (LW-XG) on the nutrition of human body are rarely investigated. Presently, body weight regulation effect of a LW-XG on male mice was assayed. Results showed that LW-XG was safe to Caco-2 cells and mice, and increased mice body weight gain from 10.78 ± 2.15 g to 13.28 ± 1.97 g. Meanwhile, the acetate, propionate, butyrate and total short-chain fatty acids (SCFAs) contents increased from 25.13 ± 1.28 μmol/g, 11.28 ± 0.81 μmol/g, 7.85 ± 0.43 μmol/g and 44.26 ± 1.85 μmol/g to 41.76 ± 1.08 μmol/g, 19.84 ± 0.97 μmol/g, 12.58 ± 0.26 μmol/g and 74.18 ± 1.72 μmol/g, respectively. Furthermore, LW-XG increased the abundance and diversity of gut microbiota, and Firmicutes/Bacteroidetes ratio was significantly increased from 0.3547 to 1.5371. |
| Databáze: | OpenAIRE |
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