Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity

Autor: Dokyoung Kim, Kyo Han Ahn, Sunderraman Sambasivan, Jin Yong Kim, Ki Hean Kim, Taiha Joo, Kyong-Tai Kim, Hyoseok Nam, Kyung-Ha Lee
Rok vydání: 2012
Předmět:
Zdroj: Chemical communications (Cambridge, England). 48(54)
ISSN: 1364-548X
Popis: Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.
Databáze: OpenAIRE