Supplementary Video S2.Time-lapse microscopy of HeLa-H2B-GFP cells treated with 6-AA (2.5, 5 and 10 nM). from 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells

Autor: Colleen C. Nelson, Rohan A. Davis, Melanie Lehman, Maria Kavallaris, Brian Gabrielli, Anja Rockstroh, Martin C. Sadowski, Claire Levrier
Rok vydání: 2023
Popis: HeLa-H2B-GFP cells were imaged using an Olympus IX81 (1 image/5 min for 24 h). Top panels: brightfield, bottom panels: GFP channel. 6-AA increased in a concentration-dependent manner mitotic duration, leading to cell death or asymmetric division. Scale bar=20 µm.
Databáze: OpenAIRE