Medication regimen complexity and prevalence of potentially inappropriate medicines in older patients after hospitalisation
| Autor: | Stefan R Kowalski, Wei Terk Chang, Christopher P Alderman, Wassana Sorich |
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| Přispěvatelé: | Chang, Wei Terk, Kowalski, Stefan R, Sorich, Wassana, Alderman, Christopher P |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Beers Criteria Pharmaceutical Science Pharmacy Inappropriate Prescribing Toxicology 030226 pharmacology & pharmacy Cohort Studies 03 medical and health sciences 0302 clinical medicine Primary outcome Medication Reconciliation Older patients medicine Prevalence medication regimen complexity index Humans Pharmacology (medical) 030212 general & internal medicine beers criteria Prescribed medications Potentially Inappropriate Medication List Aged Retrospective Studies Pharmacology Aged 80 and over business.industry Australia Potentially Inappropriate Medications Retrospective cohort study Patient Discharge Hospitalization Medication regimen potentially inappropriate medication Emergency medicine Polypharmacy Female business |
| Zdroj: | International journal of clinical pharmacy. 39(4) |
| ISSN: | 2210-7711 |
| Popis: | Background: There is a relative paucity of information to characterise potential changes in medication regimen complexity and prevalence of prescribing of potentially inappropriate medications after hospitalisation, both in Australia and elsewhere. Objective: To evaluate medication regimen complexity and the prevalence of potentially inappropriate medications before and after admission to hospital. Setting General medical units of a tertiary care hospital in Australia. Methods: Retrospective cohort study of patients aged 65 years and above. Medication complexity was measured by using the Medication Regimen Complexity Index (MRCI). Main outcome measure The primary outcome was the change in the Medication Regimen Complexity Index for all prescribed medications after hospitalization. Results: A convenience sample of 100 patients was included in the study. There was a significant change in the mean medication complexity score (as measured using the MRCI), increasing from 29 at the time of admission to 32 at the time of discharge (p < 0.05). Factors such as baseline medication regimen complexity (pre-admission MRCI) and length of stay in the hospitals appear to influence the change in medication complexity. However, the proportion of patients prescribed at least one potentially inappropriate medicine (PIM) decreased significantly, from 52% pre-hospitalization to 42% at discharge (p = 0.04). Conclusions: Relative to the time of admission, overall medication complexity increased and the proportion of patients who were prescribed PIMs decreased after hospitalisation. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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