The Origin of Cholesterol’s Condensing Effect

Autor:	Trevor A. Daly, Minghui Wang, Steven L. Regen
Jazyk:	angličtina
Rok vydání:	2011
Předmět:	1 2-Dipalmitoylphosphatidylcholine Molecular Structure Cholesterol Stereochemistry Cholestanol Condensation Surfaces and Interfaces Condensed Matter Physics Article Coprostanol chemistry.chemical_compound chemistry Computational chemistry Electrochemistry General Materials Science Spectroscopy
Popis:	The condensing effect of cholesterol on fluid bilayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine has been compared with that of dihydrocholesterol and coprostanol by means of nearest-neighbor recognition measurements. Whereas dihydrocholesterol exhibits a condensing power that is equivalent to that of cholesterol, the action of coprostanol is significantly weaker. These results provide strong support for a template mechanism of condensation and argue against an umbrella mechanism.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfa55fc087566e714d4af714fccd609 https://europepmc.org/articles/PMC3107356/ Zobrazit plný text záznamu