Hemostatic state augmented with platelet indices among Sudanese diabetic septic foot
Autor: | Mohamed Salih Ali, Bashir Abdrhman Bashir |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
DSF 030204 cardiovascular system & hematology Thrombin time Gastroenterology Sudan 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus medicine Coagulation testing Platelet indices 030212 general & internal medicine Mean platelet volume Molecular Biology Angiology Prothrombin time Coagulation medicine.diagnostic_test lcsh:RC633-647.5 business.industry Diabetes Metabolic disorder lcsh:Diseases of the blood and blood-forming organs Hematology medicine.disease business Research Article Partial thromboplastin time |
Zdroj: | BMC Hematology, Vol 18, Iss 1, Pp 1-6 (2018) BMC Hematology |
ISSN: | 2052-1839 |
DOI: | 10.1186/s12878-018-0104-5 |
Popis: | Background Diabetes mellitus is a very rampant metabolic disorder, particularly type II. It has many complications such as the septic foot. Diabetic septic foot (DSF) patients are at high risk for coagulation abnormalities as well as surgical hazards. Owing to the potential sequelae of coagulation and vascular abnormalities, this work aimed at studying the hemostatic state and platelet indices in diabetes type II patients with septic foot. Methods A case-control study was conducted during the period from July to September 2017 at Dr. Awaad medical center, Red Sea State, Sudan. 57 diabetic patients with septic foot, aged between 17 and 78 years along with 57 non-diabetic subjects as control were enrolled. Sociodemographic data were collected using a structured questionnaire. Venipuncture blood was taken with necessary safety measures. Diabetes profile, coagulation studies as well as platelet indices were estimated. Data was analyzed using SPSS version 24.0 for windows. Ethical approval was considered and written consent from each participant was obtained. Results The mean age of diabetic patients with septic foot and healthy controls were 48.49 ± 15.8 and 32.77 ± 14.0, respectively. The duration of the diabetes onset was 10.43 ± 9.5 years. Plasma prothrombin time (PT) value (12.61 ± 2.6 vs 13.67 ± 1.5, P |
Databáze: | OpenAIRE |
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