Additional file 8 of Glycogen synthase 1 targeting reveals a metabolic vulnerability in triple-negative breast cancer

Autor: de Heer, E. C., Zois, C. E., Bridges, E., van der Vegt, B., Sheldon, H., Veldman, W. A., Zwager, M. C., van der Sluis, T., Haider, S., Morita, T., Baba, O., Schröder, C. P., de Jong, S., Harris, A. L., Jalving, M.
Rok vydání: 2023
DOI: 10.6084/m9.figshare.23304892.v1
Popis: Additional file 8: Figure 6. (a) Clonogenic agarose assay of HCC1806 cells transfected with siCtrl or siGYS1, cultured in 5.6 mM glucose complete medium for 10 days in normoxia. (b) Ki67 proliferation index in spheroids of HCC1806 cells transfected with siRNA-mediated GYS1 knockdown or scrambled control. (c) Well confluency of HCC1806-shCtrl and -shGYS1 cells treated with different concentrations of GTPP, cultured in 5.6 mM glucose complete DMEM, was measured by Incucyte every 3h.
Databáze: OpenAIRE