Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet

Autor:	Jeong Keun Kim, Young Hee Lim, Sung Pil Jo
Rok vydání:	2014
Předmět:	Oral treatment Cholesterol diet Rheum undulatum Pharmaceutical Science Hyperlipidemias Pharmacology Analytical Chemistry Rats Sprague-Dawley chemistry.chemical_compound Drug Discovery Hyperlipidemia Stilbenes medicine Animals Rheum Triglycerides Hypolipidemic Agents chemistry.chemical_classification biology Rhapontigenin Cholesterol Plant Extracts Organic Chemistry Fatty liver biology.organism_classification medicine.disease Rats Fatty Liver Enzyme Complementary and alternative medicine Biochemistry chemistry Molecular Medicine
Zdroj:	Planta medica. 80(13)
ISSN:	1439-0221
Popis:	Rhapontin was purified from a methanol extract from the roots of Rheum undulatum, and rhapontigenin was produced by an enzymatic transformation of rhapontin. Rats were fed a high-cholesterol diet to induce hyperlipidemia, followed by oral treatment with rhapontin or rhapontigenin (1–5 mg/kg/day). Rhapontin and rhapontigenin treatment resulted in a significant (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cea1eed505755d03509a60b7d4ead66 https://pubmed.ncbi.nlm.nih.gov/25127020 Zobrazit plný text záznamu