Amyloid a protein amyloidosis in a patient with plasma cell dyscrasia
| Autor: | Katsumi Eguchi, Kiyoshi Migita, Satoshi Yamasaki, Keisuke Hamasaki, Hiroki Ishikawa, Yuji Kato, Tomoyuki Aritomi, Tomayoshi Hayashi, Kazuhiko Nakao, Kazuaki Ohkubo, Keisuke Nakata |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Male
Pathology medicine.medical_specialty Amyloid Plasma cell dyscrasia Paraproteinemias Peripheral blood mononuclear cell mental disorders Blood plasma Internal Medicine medicine Humans Immunoelectrophoresis Serum Amyloid A Protein Proteinuria business.industry Amyloidosis Congo Red General Medicine Hepatitis C Chronic Middle Aged medicine.disease Immunohistochemistry Magnetic Resonance Imaging Amyloid A Protein Gastric Mucosa medicine.symptom business |
| Zdroj: | Internal medicine (Tokyo, Japan). 41(5) |
| ISSN: | 0918-2918 |
| Popis: | We report a 59-year-old man who was found to have plasma cell dyscrasia and amyloid A protein (AA) amyloidosis during the follow-up period of chronic inactive hepatitis C. Clinical manifestations such as swallowing disturbance, proteinuria and leg edema were associated with AA amyloid deposits in his tongue and kidneys. Although the relationship between these two diseases remains to be determined, the ability of peripheral blood mononuclear cells to degradate serum amyloid A protein was apparently reduced in this patient, compared with normal volunteers. This would, in part, account for the AA amyloid deposition in this patient. |
| Databáze: | OpenAIRE |
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